52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

Market Overview

U.S. stocks are broadly lower today, with the Dow Jones down ⁦0.30%⁩, the S&P 500 down ⁦0.38%⁩, and the Nasdaq Composite down ⁦0.74%⁩. Market breadth is negative, with 3,486 stocks declining versus 1,624 advancing, pointing to a broadly bearish bias.

Dow Jones

52,231.89

Change

-157.86-0.30%

S&P 500

7,520.93

Change

-29.01-0.38%

Nasdaq Composite

25,065.874

Change

-187.265-0.74%

24H Gainers

1,624

24H Losers

3,486

52 Week Gainers

Large Cap Small Cap 52 Week Gainers 52 Week Losers Semiconductor Software Biotech Bank

#	Stock					52 Week Range
4601	Research Frontiers Inc.REFR	$0.36	-0.65%	92.21K	$12.66M	$0.33 - $2.10	0.00%
4602	Datacentrex, Inc.DTCX	$0.95	-6.17%	68.23K	$44.83M	$0.90 - $4.98	0.00%
4603	BitGo Holdings, Inc.BTGO	$4.26	-18.01%	2.38M	$571.27M	$4.15 - $24.50	0.00%
4604	enCore Energy Corp.EU	$0.63	-9.24%	3.25M	$123.50M	$0.62 - $3.67	0.00%
4605	Atlas Critical Minerals CorporationATCX	$2.02	-1.70%	479	$8.95M	$1.85 - $14.01	0.00%
4606	Byrna Technologies, Inc.BYRN	$4.16	+6.11%	176.87K	$97.41M	$3.17 - $20.69	0.00%
4607	PowerCompute, Inc.PWCM	$0.50	-6.16%	59.91K	$1.27M	$0.43 - $2.55	0.00%
4608	Alpha Compute Corp.ALP	$3.18	+0.76%	10.00K	$4.93M	$2.78 - $27.90	0.00%
4609	Rocket One Inc.RKTO	$0.38	-0.76%	139.17K	$9.56M	$0.37 - $2.45	0.00%
4610	Fluence Energy, Inc.FLNC	$4.91	-9.07%	6.29M	$702.22M	$4.79 - $33.51	0.00%
4611	Aclarion, Inc.ACON	$1.63	-6.86%	12.05K	$4.70M	$1.54 - $9.36	0.00%
4612	Oklo Inc.OKLO	$25.09	-5.63%	9.67M	$4.67B	$18.54 - $117.44	0.00%
4613	One and One Green Technologies. Inc.YDDL	$1.02	-1.90%	10.75K	$57.71M	$0.96 - $16.23	0.00%
4614	BioStem Technologies, Inc.BSEM	$1.03	-7.59%	426.84K	$19.23M	$1.01 - $8.40	0.00%
4615	Dermata Therapeutics, Inc.DRMA	$0.72	-7.21%	42.35K	$3.58M	$0.60 - $4.66	0.00%
4616	NervGen Pharma Corp.NGEN	$1.33	-4.66%	259.41K	$107.56M	$1.28 - $6.30	0.00%
4617	Shuttle Pharmaceuticals Holdings, Inc.SHPH	$5.37	+4.99%	5.28K	$25.56M	$2.58 - $44.40	0.00%
4618	MIND Technology, Inc.MIND	$3.04	-5.23%	88.12K	$27.68M	$3.03 - $14.50	0.00%
4619	ASP Isotopes Inc.ASPI	$1.98	-7.48%	2.78M	$302.79M	$1.66 - $9.29	0.00%
4620	Anbio BiotechnologyNNNN	$3.84	-5.88%	6.84K	$169.42M	$3.09 - $44.73	0.00%
4621	ZeroStack Corp.ZSTK	$2.61	-2.40%	2.28K	$56.86M	$1.32 - $15.04	0.00%
4622	Lightbridge Corp.LTBR	$4.54	-6.20%	593.38K	$169.87M	$3.91 - $20.99	0.00%
4623	Aurelion Inc.AURE	$1.02	-6.40%	122.45K	$19.68M	$0.85 - $5.48	0.00%
4624	WEBUY GLOBAL LTDWBUY	$0.44	-9.06%	67.99K	$2.29M	$0.43 - $4.96	0.00%
4625	First Breach Inc.FBDT	$0.91	-5.62%	81.63K	$48.02M	$0.61 - $12.00	0.00%
4626	Processa Pharmaceuticals, Inc.PCSA	$1.89	-1.03%	17.05K	$5.30M	$1.04 - $8.88	0.00%
4627	Lucid Group, Inc.LCID	$3.77	+4.72%	28.78M	$1.48B	$2.37 - $17.80	0.00%
4628	Investcorp Credit Management BDC, Inc.ICMB	$0.60	-0.78%	22.59K	$8.72M	$0.59 - $3.12	0.45%
4629	Australian Oilseeds Holdings LimitedCOOT	$0.28	-10.64%	14.75K	$13.93M	$0.26 - $1.40	0.00%
4630	Dogwood Therapeutics, Inc.DWTX	$1.21	+0.83%	92.64K	$46.22M	$0.90 - $7.04	0.00%
4631	Natural Health Trends Corp.NHTC	$0.75	+0.40%	26.62K	$6.34M	$0.70 - $4.00	0.61%
4632	PTIX	$0.00	0.00%	0	$0	$0.13 - $2.38	0.00%
4633	Vistance Networks, Inc.VISN	$4.13	+0.12%	9.70M	$951.33M	$3.90 - $19.95	0.00%
4634	Locafy LimitedLCFY	$0.85	-10.49%	7.96K	$1.91M	$0.85 - $6.20	0.00%
4635	Circle8 Group, Inc.CIRC	$0.18	-12.25%	408.68K	$20.91M	$0.17 - $0.98	0.00%
4636	Kestrel Group, Ltd.KG	$3.94	-4.72%	8.15K	$33.92M	$3.84 - $18.56	0.00%
4637	DirectBooking Technology Co., LtdZDAI	$1.40	+2.72%	6.62K	$11.16M	$1.06 - $12.00	0.00%
4638	Upland Software, Inc.UPLD	$3.83	+0.66%	70.72K	$10.86M	$2.75 - $19.60	0.00%
4639	PureCycle Technologies, Inc.PCT	$2.15	+4.37%	7.30M	$431.15M	$1.59 - $14.20	0.00%
4640	AI Financial CorporationAIFC	$0.18	-6.13%	433.18K	$25.31M	$0.16 - $1.08	0.00%
4641	DNA X, Inc.SONM	$2.35	+4.28%	12.51K	$3.50M	$2.02 - $11.90	0.00%
4642	Armlogi Holding Corp.BTOC	$1.86	-1.64%	6.86K	$5.29M	$1.74 - $11.49	0.00%
4643	FTC Solar, Inc.FTCI	$1.54	-3.14%	971.88K	$28.25M	$1.17 - $12.75	0.00%
4644	Rail Vision Ltd.RVSN	$2.56	-10.97%	49.32K	$5.60M	$2.50 - $13.54	0.00%
4645	York Space Systems Inc.YSS	$7.00	+0.56%	988.78K	$859.86M	$5.26 - $44.54	0.00%
4646	Imunon, Inc.IMNN	$0.78	-12.10%	240.86K	$4.38M	$0.78 - $4.38	0.00%
4647	Haoxin Holdings LimitedHXHX	$0.15	+2.04%	58.33K	$1.54M	$0.12 - $1.47	0.00%
4648	Health In Tech, Inc.HIT	$0.60	-1.02%	46.98K	$32.43M	$0.49 - $3.05	0.00%
4649	Smartbird, Inc.BIRD	$1.24	-8.15%	259.14K	$11.55M	$1.23 - $24.31	0.00%
4650	Pulsenmore Ltd.PLSM	$1.52	-2.56%	15.82K	$9.82M	$1.42 - $12.97	0.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?

These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.

How is the 52-week gain calculated?

It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.

Which stock has gained the most over 52 weeks?

Research Frontiers Inc. (REFR) currently leads with a 52-week gain of 76.88% as of 2026-11-11 03:49 UTC.

Why use a 52-week stock performance ranking?

It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.

Does strong 52-week performance guarantee future gains?

No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.

How is this different from the daily Top Gainers list?

The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

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Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.