Dow Jones
52,054.4
Change
-335.35-0.64%
52-Week Top Gaining U.S. stocks
Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.
Market Overview
U.S. stocks are broadly lower today, with the Dow Jones down 0.64%, the S&P 500 down 0.63%, and the Nasdaq Composite down 0.75%. Market breadth is negative, with 4,109 stocks declining versus 1,001 advancing, pointing to a broadly bearish bias.
S&P 500
7,502.08
Change
-47.86-0.63%
Nasdaq Composite
25,064.165
Change
-188.974-0.75%
24H Gainers
1,001
24H Losers
4,109
52 Week Gainers
| # | Stock | 52 Week Range | |||||
|---|---|---|---|---|---|---|---|
| 1 | Eloxx Pharmaceuticals, Inc.ELOX | $13.21 | -0.75% | 3.74K | $53.32M | $12.93 - $23.40 | 0.00% |
| 2 | Mega Fortune Company LimitedMGRT | $120.00 | -3.35% | 831 | $1.65B | $4.04 - $170.00 | 0.00% |
| 3 | Bank of New York Mellon CorporationBNY | $152.32 | +0.45% | 209.85K | $102.49B | $10.05 - $165.84 | 0.02% |
| 4 | Nine Energy Service, Inc.NINE | $7.00 | +7.29% | 6.24K | $103.79M | $0.29 - $13.23 | 0.00% |
| 5 | TJGC Group LimitedTJGC | $31.64 | -3.18% | 68.09K | $319.51M | $1.46 - $36.76 | 0.00% |
| 6 | Moderna, Inc.MRNA | $256.05 | -2.92% | 3.01M | $102.22B | $22.28 - $280.80 | 0.00% |
| 7 | STAK Inc.STAK | $4.41 | +5.62% | 636.97K | $62.63M | $0.29 - $12.00 | 0.00% |
| 8 | Erasca, Inc.ERAS | $15.62 | -0.93% | 937.34K | $5.46B | $2.21 - $24.28 | 0.00% |
| 9 | agilon health, inc.AGL | $111.97 | -2.11% | 18.15K | $1.88B | $7.48 - $133.04 | 0.00% |
| 10 | Climb Bio, Inc.CLYM | $11.49 | +3.18% | 76.63K | $663.30M | $1.64 - $18.33 | 0.00% |
| 11 | BUUU Group LimitedBUUU | $4.79 | -2.94% | 10.33K | $1.05B | $0.57 - $8.10 | 0.00% |
| 12 | Kodiak Sciences Inc.KOD | $107.21 | -0.32% | 129.30K | $6.74B | $18.05 - $109.17 | 0.00% |
| 13 | SELLAS Life Sciences Group, Inc.SLS | $8.66 | +0.52% | 883.47K | $1.75B | $1.39 - $15.88 | 0.00% |
| 14 | Space Exploration Technologies Corp.SPCX | $144.62 | +1.14% | 24.58M | $1.82T | $21.32 - $225.64 | 0.00% |
| 15 | CareDx, Inc.CDNA | $83.70 | -0.05% | 130.38K | $4.40B | $15.15 - $90.87 | 0.00% |
| 16 | Vince Holding Corp.VNCE | $13.12 | +2.37% | 58.08K | $169.87M | $1.95 - $13.90 | 0.00% |
| 17 | Spyre Therapeutics, Inc.SYRE | $106.86 | -1.41% | 102.61K | $10.15B | $21.63 - $110.64 | 0.00% |
| 18 | New Century Logistics (BVI) LimitedNCEW | $17.25 | +0.26% | 63 | $55.20M | $2.80 - $20.83 | 0.00% |
| 19 | Anterix Inc.ATEX | $79.16 | +0.28% | 26.14K | $1.55B | $17.82 - $113.00 | 0.00% |
| 20 | Twist Bioscience CorporationTWST | $134.43 | -0.07% | 183.71K | $8.43B | $23.30 - $219.71 | 0.00% |
| 21 | Avita Medical, Inc.RCEL | $17.20 | -0.47% | 85.67K | $540.58M | $3.22 - $18.43 | 0.00% |
| 22 | Fossil Group, Inc.FOSL | $8.11 | -1.24% | 49.65K | $479.31M | $1.70 - $8.25 | 0.00% |
| 23 | AXT Inc.AXTI | $41.80 | -1.91% | 2.44M | $2.74B | $8.44 - $143.16 | 0.00% |
| 24 | Energys Group LimitedENGS | $4.71 | -0.32% | 1.63M | $254.90M | $0.57 - $5.00 | 0.00% |
| 25 | Q32 Bio Inc.QTTB | $9.65 | +2.84% | 47.30K | $288.89M | $1.91 - $23.57 | 0.00% |
| 26 | Veradermics, IncorporatedMANE | $149.77 | +4.08% | 134.80K | $5.80B | $32.00 - $152.35 | 0.00% |
| 27 | Eton Pharmaceutcials, Inc.ETON | $66.97 | +1.74% | 233.00K | $1.93B | $14.27 - $66.98 | 0.00% |
| 28 | PACS Group, Inc.PACS | $48.84 | +0.02% | 38.74K | $7.75B | $10.31 - $51.68 | 0.01% |
| 29 | 10x Genomics, Inc.TXG | $65.15 | -0.38% | 447.86K | $7.83B | $15.12 - $102.81 | 0.00% |
| 30 | Oruka Therapeutics, Inc.ORKA | $104.51 | -0.48% | 125.29K | $6.92B | $25.23 - $115.52 | 0.00% |
| 31 | GIBO Holdings LimitedGIBO | $170.75 | -4.48% | 2.30K | $456.50M | $22.60 - $194.91 | 0.00% |
| 32 | MaxLinear, Inc.MXL | $55.44 | -0.93% | 687.09K | $5.04B | $12.77 - $128.30 | 0.00% |
| 33 | Pulse Biosciences, Inc.PLSE | $55.37 | -2.13% | 50.96K | $4.07B | $12.56 - $58.94 | 0.00% |
| 34 | Alpha Tau Medical Ltd.DRTS | $13.95 | +0.36% | 81.80K | $1.26B | $3.43 - $15.79 | 0.00% |
| 35 | Iovance Biotherapeutics, Inc.IOVA | $8.37 | +0.86% | 1.90M | $3.79B | $2.08 - $15.37 | 0.00% |
| 36 | OmniAb, Inc.OABI | $5.26 | +0.19% | 117.66K | $767.81M | $1.35 - $5.45 | 0.00% |
| 37 | Nuvectis Pharma, Inc.NVCT | $21.16 | +1.99% | 38.74K | $727.77M | $5.77 - $29.27 | 0.00% |
| 38 | Vera Bradley, Inc.VRA | $8.13 | +0.50% | 142.36K | $233.21M | $1.39 - $8.35 | 0.00% |
| 39 | AN2 Therapeutics, Inc.ANTX | $4.08 | +0.12% | 65.25K | $153.93M | $1.00 - $7.19 | 0.00% |
| 40 | MindForge Inc.MF | $14.58 | +11.62% | 102.01K | $67.76M | $3.80 - $25.90 | 0.00% |
| 41 | Sandisk CorporationSNDK | $901.67 | -0.03% | 3.70M | $118.82B | $183.00 - $2,354.39 | 0.00% |
| 42 | Quhuo LimitedQH | $2.83 | -0.18% | 637 | $7.43M | $0.07 - $12.81 | 0.00% |
| 43 | ImmunityBio, Inc.IBRX | $7.17 | +2.65% | 3.07M | $7.59B | $1.95 - $12.43 | 0.00% |
| 44 | Century Therapeutics, Inc.IPSC | $1.81 | +2.25% | 47.45K | $328.65M | $0.43 - $3.04 | 0.00% |
| 45 | Relay Therapeutics, Inc.RLAY | $20.35 | +0.29% | 279.55K | $4.50B | $5.95 - $21.27 | 0.00% |
| 46 | Ampco-Pittsburgh Corp.AP | $6.34 | +4.00% | 14.56K | $130.93M | $1.75 - $12.81 | 0.00% |
| 47 | Absci CorporationABSI | $10.78 | -0.56% | 355.65K | $1.85B | $2.24 - $12.54 | 0.00% |
| 48 | Entravision CommunicationEVC | $9.19 | -0.75% | 109.89K | $762.18M | $2.56 - $13.74 | 0.02% |
| 49 | Revolution Medicines, Inc.RVMD | $196.96 | -1.69% | 223.08K | $42.60B | $61.50 - $224.31 | 0.00% |
| 50 | RF Acquisition Corp IIRFAI | $33.27 | +6.07% | 205 | $116.86M | $8.94 - $73.00 | 0.00% |
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Frequently Asked Questions (FAQ)
What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Eloxx Pharmaceuticals, Inc. (ELOX) currently leads with a 52-week gain of 1,228,445.45% as of 2026-11-10 23:07 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.
Discover Top US Stocks
Apple Inc.AAPLAlphabet Inc.GOOGTesla, Inc.TSLAEli Lilly & Co.LLYAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGTesla, Inc.TSLAEli Lilly & Co.LLYAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGTesla, Inc.TSLAEli Lilly & Co.LLYAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGTesla, Inc.TSLAEli Lilly & Co.LLYAdvanced Micro DevicesAMDABBVIE INC.ABBV
Apple Inc.AAPLAlphabet Inc.GOOGTesla, Inc.TSLAEli Lilly & Co.LLYAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGTesla, Inc.TSLAEli Lilly & Co.LLYAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGTesla, Inc.TSLAEli Lilly & Co.LLYAdvanced Micro DevicesAMDABBVIE INC.ABBVApple Inc.AAPLAlphabet Inc.GOOGTesla, Inc.TSLAEli Lilly & Co.LLYAdvanced Micro DevicesAMDABBVIE INC.ABBV
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Microsoft Corp.MSFTSpace Exploration Technologies Corp.SPCXBerkshire Hathaway Inc.BRK.AVISA Inc.VJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXBerkshire Hathaway Inc.BRK.AVISA Inc.VJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXBerkshire Hathaway Inc.BRK.AVISA Inc.VJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXBerkshire Hathaway Inc.BRK.AVISA Inc.VJohnson & JohnsonJNJChevron CorporationCVX
Microsoft Corp.MSFTSpace Exploration Technologies Corp.SPCXBerkshire Hathaway Inc.BRK.AVISA Inc.VJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXBerkshire Hathaway Inc.BRK.AVISA Inc.VJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXBerkshire Hathaway Inc.BRK.AVISA Inc.VJohnson & JohnsonJNJChevron CorporationCVXMicrosoft Corp.MSFTSpace Exploration Technologies Corp.SPCXBerkshire Hathaway Inc.BRK.AVISA Inc.VJohnson & JohnsonJNJChevron CorporationCVX
Alphabet Inc.GOOGLMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BMicron Technology, Inc.MUMastercard IncorporatedMACoca-Cola CompanyKOAlphabet Inc.GOOGLMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BMicron Technology, Inc.MUMastercard IncorporatedMACoca-Cola CompanyKOAlphabet Inc.GOOGLMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BMicron Technology, Inc.MUMastercard IncorporatedMACoca-Cola CompanyKOAlphabet Inc.GOOGLMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BMicron Technology, Inc.MUMastercard IncorporatedMACoca-Cola CompanyKO
Alphabet Inc.GOOGLMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BMicron Technology, Inc.MUMastercard IncorporatedMACoca-Cola CompanyKOAlphabet Inc.GOOGLMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BMicron Technology, Inc.MUMastercard IncorporatedMACoca-Cola CompanyKOAlphabet Inc.GOOGLMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BMicron Technology, Inc.MUMastercard IncorporatedMACoca-Cola CompanyKOAlphabet Inc.GOOGLMeta Platforms, Inc.METABERKSHIRE HATHAWAYBRK.BMicron Technology, Inc.MUMastercard IncorporatedMACoca-Cola CompanyKO
Disclaimer
US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.