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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are broadly lower today, with the Dow Jones down ⁦0.30%⁩, the S&P 500 down ⁦0.38%⁩, and the Nasdaq Composite down ⁦0.74%⁩. Market breadth is negative, with 3,480 stocks declining versus 1,630 advancing, pointing to a broadly bearish bias.

Dow Jones
52,231.89
Change
-157.86-0.30%
S&P 500
7,520.93
Change
-29.01-0.38%
Nasdaq Composite
25,065.874
Change
-187.265-0.74%
24H Gainers
1,630
24H Losers
3,480

52 Week Gainers

#Stock52 Week Range
4651iTonic Holdings LtdITOC$2.01+12.97%39.24K$13.73M$1.63 - $18.400.00%
4652Aqua Metals, Inc.AQMS$1.45-5.33%67.15K$5.16M$1.02 - $8.390.00%
4653RenX Enterprises Corp.RENX$1.04+0.47%37.21K$3.61M$0.84 - $7.000.00%
4654DocGo Inc.DCGO$0.23-10.44%1.89M$22.36M$0.21 - $1.170.00%
4655Soluna Holdings, Inc.SLNH$0.52-4.52%3.73M$128.53M$0.45 - $2.760.02%
4656Teads Holding CoTEAD$0.20-1.59%460.30K$19.42M$0.16 - $1.420.00%
4657Tilray Brands, Inc.TLRY$2.65-6.84%4.07M$392.38M$2.48 - $15.700.00%
4658Acurx Pharmaceuticals, Inc.ACXP$1.06-1.89%62.38K$5.92M$0.95 - $7.540.00%
4659Globavend Holdings LimitedGVH$0.91-2.55%14.90K$3.92M$0.77 - $6.460.00%
4660Exascale Labs Holdings Inc.XLAB$1.03-7.59%1.11M$96.50M$0.78 - $7.390.00%
4661OSR Health, Inc.OSRH$0.12-53.28%22.28M$0$0.07 - $0.900.00%
4662Polestar Automotive Holding UK PLCPSNY$4.61-2.33%101.22K$752.08M$3.22 - $24.400.00%
4663CervoMed Inc.CRVO$1.38-3.50%185.80K$20.85M$1.27 - $10.000.00%
4664Alset Inc.AEI$0.49+1.43%4.24K$18.98M$0.47 - $3.980.00%
4665CollPlant Biotechnologies LtdCLGN$3.90-7.23%22.03K$7.38M$2.64 - $22.500.00%
4666Bakkt, Inc.BKKT$4.17-10.11%1.22M$66.38M$3.86 - $25.000.00%
4667Terrestrial Energy Inc.IMSR$2.73-9.17%2.50M$301.01M$2.44 - $14.290.00%
4668Nakamoto Inc.NAKA$5.86-2.06%75.77K$107.46M$3.33 - $32.040.00%
4669Intelligent Group LimitedINTJ$2.22-9.06%9.04K$5.24M$2.17 - $12.520.00%
4670Guardforce AI Co., LimitedGFAI$0.17-4.79%46.65K$5.53M$0.17 - $0.980.00%
4671Caribou Biosciences, Inc.CRBU$0.41-4.69%1.51M$44.19M$0.39 - $2.490.00%
4672TEN Holdings, Inc.XHLD$0.85-1.64%1.75M$6.97M$0.38 - $15.430.00%
4673Cogent Communications Holdings, Inc.CCOI$4.34-2.36%1.65M$222.53M$3.56 - $28.700.27%
4674Prairie Operating CoPROP$0.36-0.86%594.64K$41.17M$0.32 - $2.550.00%
4675Compass Therapeutics, Inc.CMPX$0.83+0.30%1.89M$150.19M$0.67 - $6.880.00%
4676Cerenome, Inc.CNSY$0.68+19.16%1.11M$5.19M$0.43 - $4.250.00%
4677Bone Biologics Corp.BBLG$0.33-4.00%31.11K$1.13M$0.32 - $2.390.00%
4678Psyence Biomedical LtdPBM$2.99-0.43%25.78K$11.39M$1.92 - $18.620.00%
4679ThredUp Inc.TDUP$1.49+9.16%1.59M$167.48M$1.24 - $8.760.00%
4680Loop Industries, Inc.LOOP$0.25+11.96%47.49K$12.15M$0.24 - $1.540.00%
4681Aptera Motors Corp.SEV$1.61-29.39%1.50M$86.37M$1.29 - $8.800.00%
4682BOXABL, Inc.BXBL$1.87-0.53%102.75K$466.20M$1.76 - $11.990.00%
4683Xtend AI Robotics, Inc.XTND$1.18+3.98%2.08M$248.43M$0.80 - $7.150.00%
4684Freightos LimitedCRGO$0.76+7.91%92.25K$39.80M$0.58 - $4.240.00%
4685Upexi, Inc.UPXI$0.63-4.64%960.83K$55.82M$0.54 - $3.650.00%
4686Odyssey Marine Exploration, Inc.OMEX$10.36-4.19%10.94K$24.32M$9.59 - $66.750.00%
4687NeuroOne Medical Technologies CorporationNMTC$0.80-11.88%135.27K$7.27M$0.76 - $6.120.00%
4688SANGRIX INC.SGRX$0.40-12.33%300.05K$1.59M$0.30 - $3.440.00%
4689MacKenzie Realty Capital, Inc.MKZR$0.93-5.00%1.72K$2.58M$0.83 - $5.220.00%
4690SunCar Technology Group Inc.SDA$0.36-18.18%6.46M$21.34M$0.13 - $2.450.00%
4691Incannex Healthcare LimitedIXHL$2.02-7.76%180.07K$25.40M$1.97 - $14.910.00%
4692Corteva, Inc.CTVA$12.17+0.50%8.59M$8.12B$11.24 - $90.970.06%
4693DarioHealth Corp.DRIO$2.40+19.66%53.70K$23.47M$1.78 - $14.770.00%
4694Creative Medical Technology Holdings, Inc.CELZ$0.60-1.00%32.98K$3.98M$0.59 - $4.720.00%
4695Ucommune International LtdUK$1.61+0.62%1.45K$1.07M$1.39 - $10.500.00%
4696NuScale Power CorporationSMR$5.22-3.57%33.64M$2.14B$4.28 - $32.090.00%
4697Avax One Technology LtdAVX$4.03-0.96%145.75K$29.83M$2.81 - $31.800.00%
4698Elicio Therapeutics, Inc.ELTX$1.61-2.13%177.21K$45.52M$1.25 - $16.000.00%
4699Eightco Holdings Inc.ORBS$0.72-1.57%7.10M$300.72M$0.57 - $4.670.00%
4700LASE Corp.LASE$0.58-3.46%519.53K$29.10M$0.38 - $4.490.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
iTonic Holdings Ltd (ITOC) currently leads with a 52-week gain of 79.39% as of 2026-11-11 03:05 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.