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52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are broadly lower today, with the Dow Jones down ⁦0.30%⁩, the S&P 500 down ⁦0.38%⁩, and the Nasdaq Composite down ⁦0.74%⁩. Market breadth is negative, with 3,480 stocks declining versus 1,630 advancing, pointing to a broadly bearish bias.

Dow Jones
52,231.89
Change
-157.86-0.30%
S&P 500
7,520.93
Change
-29.01-0.38%
Nasdaq Composite
25,065.874
Change
-187.265-0.74%
24H Gainers
1,630
24H Losers
3,480

52 Week Gainers

#Stock52 Week Range
4251Humacyte, Inc.HUMA$0.57+24.80%11.92M$157.51M$0.34 - $1.520.00%
4252Forge Nano Holdings Inc.NANO$4.24-0.71%46.40K$545.50M$3.12 - $11.960.00%
4253Global Engine Group Holding LimitedGLE$2.22-0.85%3.46K$5.44M$1.42 - $10.800.00%
4254Digi Power X Inc.DGXX$2.06-8.04%1.74M$209.18M$1.77 - $9.200.00%
4255ZOOZ Strategy Ltd.ZOOZ$5.36-3.51%5.18K$42.88M$4.55 - $13.450.00%
4256Stran & Company, Inc.SWAG$1.280.00%1.97K$23.86M$1.21 - $3.500.00%
4257Cytosorbents Corp.CTSO$6.03+3.88%6.84K$18.99M$2.84 - $17.000.00%
4258Ebang International Holdings Inc.EBON$1.73+4.85%780$8.63M$1.35 - $4.490.00%
4259ZILLOW GROUP INC.ZG$29.46-5.39%808.49K$1.22B$27.25 - $74.800.00%
4260ERock, Inc.EROC$7.80-5.09%813.29K$343.00M$6.41 - $20.700.00%
4261SCHMID Group N.VSHMD$2.47+0.61%563.75K$164.60M$2.09 - $10.650.00%
4262TH International LimitedTHCH$1.08-12.85%6.74K$44.85M$1.00 - $2.730.00%
4263QVC Group, Inc.QVCG$8.10-2.72%35.02K$377.00M$6.80 - $20.000.00%
4264GrabAGun Digital Holdings Inc.PEW$1.83-1.60%145.95K$55.49M$1.79 - $4.450.00%
4265Optimum Communications, Inc.OPTU$0.74-7.11%2.64M$202.52M$0.48 - $2.140.00%
4266Spero Therapeutics, Inc.SPRO$1.03-3.27%67.78K$60.27M$0.96 - $3.080.00%
4267NeOnc Technologies Holdings, Inc.NTHI$4.20+12.43%273.20K$109.89M$2.50 - $12.000.00%
4268Burford Capital LimitedBUR$3.69-0.13%672.19K$811.41M$2.86 - $10.100.08%
4269Rezolute, Inc.RZLT$4.09+5.68%776.34K$396.10M$1.07 - $11.460.00%
4270Spruce Biosciences, Inc.SPRB$47.56-5.25%35.82K$136.69M$38.06 - $129.000.00%
4271United States Antimony CorporationUAMY$3.15-8.79%3.98M$472.21M$2.53 - $12.640.00%
4272Franklin Wireless Corp.FKWL$2.10-0.90%91$24.70M$2.09 - $5.190.02%
4273Coinbase Global, Inc.COIN$130.63-3.88%4.55M$29.23B$129.50 - $324.800.00%
4274INNIO N.V.INIO$13.68-7.78%1.89M$10.33B$12.95 - $42.950.00%
4275Stellantis N.V.STLA$4.25-3.51%25.60M$12.87B$3.92 - $12.220.00%
4276Exyn Technologies, Inc.EXYN$2.13-3.39%44.80K$17.82M$1.50 - $7.200.00%
4277FBS Global LimitedFBGL$2.25+1.26%6.70K$2.94M$2.04 - $14.000.00%
4278Fair Isaac CorporationFICO$718.52-0.65%143.64K$15.52B$586.05 - $1,858.910.00%
4279Ballard Power Systems Inc.BLDP$1.46-5.73%1.17M$511.54M$1.40 - $6.570.00%
4280TMC the metals company Inc.TMC$2.42-7.82%2.54M$1.07B$1.91 - $10.050.00%
4281Figma, Inc.FIG$18.14-5.90%5.36M$10.08B$16.60 - $45.420.00%
4282CytoMed Therapeutics LimitedGDTC$0.80-3.71%5.62K$9.51M$0.68 - $2.290.00%
4283Biomea Fusion, Inc.BMEA$0.56-5.58%390.12K$40.45M$0.54 - $2.240.00%
4284Evommune, Inc.EVMN$7.85+1.96%259.87K$241.34M$4.94 - $33.200.00%
4285Celularity Inc.CELU$0.72-4.50%75.10K$23.33M$0.56 - $2.550.00%
4286ARS Pharmaceuticals, Inc.SPRY$3.60+14.13%1.25M$362.40M$2.44 - $13.150.00%
4287ProKidney Corp.PROK$1.09-6.96%449.21K$228.83M$0.87 - $2.950.00%
4288Texxon Holding LimitedNPT$1.690.00%3.13K$37.49M$1.14 - $22.380.00%
4289Snail, Inc.SNAL$2.05-1.44%9.83K$6.57M$1.70 - $10.800.00%
4290Inter & Co. Inc.INTR$3.88-2.88%3.03M$1.26B$3.75 - $10.360.00%
4291Aether Holdings, Inc.ATHR$2.37-5.40%1.72K$28.88M$1.87 - $6.860.00%
4292Eikon Therapeutics, Inc.EIKN$6.05+2.39%216.70K$319.57M$5.01 - $17.400.00%
4293Vulcan Infrastructure and Power Inc.VIP$0.99-3.43%87.58K$15.49M$0.95 - $2.790.00%
4294Waton Financial LimitedWTF$2.01+4.71%4.67K$95.27M$1.76 - $6.330.00%
4295BigBear.ai Holdings, Inc.BBAI$2.29-6.33%11.94M$1.10B$2.07 - $7.400.00%
4296eGain CorporationEGAN$6.09-1.54%79.43K$154.28M$5.02 - $15.950.00%
4297Veea Inc.VEEA$4.45-4.43%32.19K$15.21M$1.34 - $16.440.00%
4298O-I Glass, Inc.OI$5.13-1.91%797.67K$790.50M$4.83 - $16.910.00%
4299AIRO Group Holdings, Inc.AIRO$5.51-2.29%83.78K$164.41M$4.53 - $14.220.00%
4300Coastal Financial CorporationCCB$42.75-2.32%47.81K$653.55M$35.56 - $120.050.00%

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Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Humacyte, Inc. (HUMA) currently leads with a 52-week gain of 58.00% as of 2026-11-11 06:18 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.