Buy Crypto
Markets
Spot
FuturesBTC
Earn
Event Center
Rewards Hub
More
100%+ PoR

52-Week Top Losing U.S. stocks

Track U.S. stocks with the largest price declines over the past 52 weeks on MEXC. Stocks are ranked by 52-week percentage change from lowest to highest.

52-Week Top Losing U.S. stocks

Market Overview

U.S. stocks are broadly lower today, with the Dow Jones down ⁦0.30%⁩, the S&P 500 down ⁦0.38%⁩, and the Nasdaq Composite down ⁦0.74%⁩. Market breadth is negative, with 3,480 stocks declining versus 1,630 advancing, pointing to a broadly bearish bias.

Dow Jones
52,231.89
Change
-157.86-0.30%
S&P 500
7,520.93
Change
-29.01-0.38%
Nasdaq Composite
25,065.874
Change
-187.265-0.74%
24H Gainers
1,630
24H Losers
3,480

52 Week Losers

#Stock52 Week Range
651Urban One, Inc.UONE$3.45-14.16%27.33K$2.12M$3.32 - $16.940.00%
652Pulmatrix, Inc.PULM$1.39+2.58%8.73K$5.08M$1.06 - $4.980.00%
653Estrella Immunopharma, Inc.ESLA$0.76+46.94%3.68M$33.19M$0.24 - $3.000.00%
654Vyome Holdings, Inc.HIND$1.57-4.80%4.16K$10.99M$1.53 - $5.880.00%
655SelectQuote, Inc.SLQT$0.46+9.68%485.47K$82.36M$0.30 - $1.760.00%
656enVVeno Medical CorporationNVNO$6.64-2.41%10.76K$4.61M$6.06 - $24.500.00%
657Largo Inc.LGO$0.34-4.37%262.98K$38.57M$0.31 - $1.930.00%
658Ohmyhome LimitedOMH$16.92-24.57%24.16M$15.67M$2.05 - $109.500.00%
659Cuprina Holdings (Cayman) LimitedCUPR$1.79-4.32%43.11K$9.36M$1.45 - $14.800.00%
660OFS Credit Company, Inc.OCCI$1.43-5.96%282.02K$41.97M$1.40 - $5.150.00%
661XORTX Therapeutics Inc.XRTX$0.86+1.76%9.89K$1.57M$0.83 - $3.600.00%
662Serve Robotics Inc.SERV$3.10-8.41%4.50M$269.23M$2.25 - $16.080.00%
663Neonode Inc.NEON$0.70+3.07%96.79K$11.71M$0.56 - $2.480.00%
664Gaia, Inc.GAIA$1.27-2.34%48.53K$25.41M$1.16 - $4.480.00%
665Apartment Investment and Management CompanyAIV$1.57+2.61%2.66M$228.75M$1.48 - $6.041.85%
666Yueda Digital HoldingYDKG$0.95-6.99%66.26K$5.31M$0.73 - $3.810.00%
667CN Energy Group Inc.CNEY$0.51-3.56%73.97K$5.98M$0.31 - $2.630.00%
668TOWNSQUARE MEDIA, INC.TSQ$1.59-9.14%230.62K$26.96M$1.59 - $7.970.48%
669StubHub Holdings, Inc.STUB$5.64-4.27%9.44M$2.35B$5.21 - $19.860.00%
670Vroom, Inc.VRM$7.14+5.11%12.25K$34.18M$6.28 - $27.750.00%
671Blink Charging CoBLNK$0.48-6.50%1.61M$69.55M$0.38 - $1.700.00%
672TurboGen Ltd.TRBG$3.51-7.65%362.18K$79.99M$2.98 - $33.990.00%
673BIO-key International, Inc.BKYI$2.38+0.84%70.58K$4.84M$1.55 - $11.100.00%
674Beam GlobalBEEM$0.69-5.96%244.71K$15.59M$0.68 - $2.400.00%
675Azio AI Holdings, Inc.AZIO$0.56-1.67%184.75K$9.67M$0.45 - $2.060.00%
676Intensity Therapeutics, Inc.INTS$3.15+3.49%8.29K$10.27M$2.80 - $15.000.00%
677SenesTech, Inc.SNES$1.04-7.02%35.59K$5.67M$0.55 - $3.610.00%
678ITG, Inc.ITG$5.32-1.02%311.71K$221.63M$4.12 - $19.260.00%
679Greenwave Technology Solutions, Inc.GWAV$2.03-0.10%3.44K$6.06M$1.91 - $8.500.00%
680Cerebras Systems Inc.CBRS$93.57-1.98%7.32M$21.30B$77.84 - $386.340.00%
681BeyondSpring Inc.BYSI$0.58-2.45%68.35K$23.89M$0.42 - $2.440.00%
682BTCS Inc.BTCS$0.94-4.09%143.17K$49.32M$0.83 - $3.630.05%
683Massimo GroupMAMO$0.96+1.27%13.86K$39.85M$0.66 - $5.590.00%
684BTC Digital Ltd.BTCT$0.62-3.44%150.90K$10.46M$0.43 - $2.750.00%
685Niagen Bioscience, Inc.NAGE$2.15-5.70%385.25K$169.88M$2.04 - $7.280.00%
686Rani Therapeutics Holdings, Inc.RANI$0.56-1.58%521.28K$64.87M$0.51 - $2.150.00%
687Super League Enterprise, Inc.SLE$4.25-4.22%78.50K$7.20M$2.12 - $17.400.00%
688Vital Farms, Inc.VITL$10.01-0.50%1.51M$429.66M$7.95 - $36.090.00%
689Boost Run Inc.BRUN$6.38-5.00%1.96M$484.08M$5.40 - $42.000.00%
690Delixy Holdings LimitedDLXY$1.57-5.99%15.19K$4.61M$1.34 - $22.250.00%
691Nano Labs LtdNA$1.39+1.84%37.78K$28.58M$1.30 - $5.160.00%
692Tigo Energy, Inc.TYGO$0.69-9.20%375.49K$53.54M$0.68 - $5.330.00%
693Nano Nuclear Energy Inc.NNE$11.58-7.29%1.37M$621.61M$9.29 - $41.500.00%
694Fusion Fuel Green PLCHTOO$1.25+1.68%21.77K$9.36M$1.11 - $5.080.00%
695Beeline Holdings, Inc.BLNE$0.65+7.18%340.96K$21.04M$0.58 - $3.730.00%
696Local Bounti CorporationLOCL$0.79-2.78%14.16K$18.38M$0.75 - $3.130.00%
697American Battery Technology CompanyABAT$1.31-7.39%1.48M$187.49M$1.14 - $5.330.00%
698Empery Digital Inc.EMPD$2.01-0.74%350.12K$56.63M$1.92 - $6.610.00%
699Caring Brands, Inc.CABR$0.94-5.94%251.04K$10.68M$0.60 - $4.390.00%
700Factorial Energy Inc.FAC$4.25-4.70%215.02K$454.85M$3.87 - $25.330.00%

BTC $81K: Catch the Next Move

Track ETH, SOL & TON rotation signals

BTC $81K: Catch the Next Move

Trade U.S. stocks Your Way on MEXC

RealStocksTokenized StocksStock Futures
What it isRealStocks — real shares of U.S.-listed companiesBlockchain-based tokens linked to U.S. stocks/ETFsUSDT-margined futures on U.S. stock price movements
OwnershipYes — actual sharesNo — synthetic exposure onlyNo — derivative exposure only
Shareholder rightsYes (e.g. dividends)NoNo
Trading hoursU.S. market sessions (pre-market, regular, after-hours, overnight)24/7Up to 24/7 (supported pairs)
Position typesBuy and holdBuy and holdLong, short, leveraged
Best forLong-term investors seeking ownership and dividend incomeTraders wanting round-the-clock access to stock exposure without holding sharesActive/short-term traders looking to speculate or hedge with leverage

Why Trade U.S. stocks on MEXC?

RealStocks, Real Ownership

Buy real US-listed shares through MEXC's partner licensed broker and receive applicable shareholder benefits, including dividends.

7,000+ U.S. stocks & ETFs

Access 7,000+ US-listed stocks and ETFs across technology, finance, healthcare, consumer sectors, and more.

Seamless USDT-to-Stock Access

Transfer USDT and convert between USDT and USD to fund your RealStocks account with ease.

Lower-Cost Stock Trading

Trade real U.S. stocks with competitive costs and keep more capital available for your investment strategy.

Frequently Asked Questions (FAQ)

What are 52-week top losing U.S. stocks?
These are U.S. stocks that have recorded some of the largest price declines over the past 52 weeks.
How is the 52-week decline measured?
It compares the latest available stock price with its price around 52 weeks earlier and calculates the percentage change.
Which stock has fallen the most over 52 weeks?
Urban One, Inc. (UONE) currently shows a 52-week decline of 71.24% as of 2026-11-11 03:49 UTC.
Why track 52-week stock losers?
The ranking helps identify stocks facing prolonged price weakness and provides a starting point for further company and valuation research.
Is a 52-week loser automatically a value stock?
No. A lower stock price does not necessarily mean a company is undervalued, so valuation and fundamental data should be reviewed separately.
How is this different from Top Losers?
52-Week Losers measures longer-term performance, while Top Losers focuses on shorter-term market declines.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.