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52-Week Top Losing U.S. stocks

Track U.S. stocks with the largest price declines over the past 52 weeks on MEXC. Stocks are ranked by 52-week percentage change from lowest to highest.

52-Week Top Losing U.S. stocks

Market Overview

U.S. stocks are broadly lower today, with the Dow Jones down ⁦0.33%⁩, the S&P 500 down ⁦0.46%⁩, and the Nasdaq Composite down ⁦0.87%⁩. Market breadth is negative, with 3,589 stocks declining versus 1,521 advancing, pointing to a broadly bearish bias.

Dow Jones
52,215.36
Change
-174.39-0.33%
S&P 500
7,514.43
Change
-35.51-0.46%
Nasdaq Composite
25,032.917
Change
-220.222-0.87%
24H Gainers
1,521
24H Losers
3,589

52 Week Losers

#Stock52 Week Range
5101Butterfly Network, Inc.BFLY$6.51-2.40%3.66M$1.60B$1.90 - $10.210.00%
5102Tilly's Inc.TLYS$4.12-2.61%129.84K$95.92M$1.14 - $6.250.00%
5103Bandwidth Inc.BAND$43.58+4.12%467.92K$1.33B$12.50 - $79.080.00%
5104American Well CorporationAMWL$12.05-3.53%143.45K$187.59M$3.71 - $15.160.00%
5105Prelude Therapeutics IncorporatedPRLD$3.77+0.13%336.49K$300.62M$1.17 - $6.830.00%
5106Absci CorporationABSI$9.96-7.73%3.81M$1.71B$2.24 - $12.540.00%
5107Rallybio CorporationRLYB$15.77-0.99%16.96K$84.88M$3.67 - $17.570.00%
5108SAIHEAT LimitedSAIH$22.31+6.34%4.44K$26.67M$5.90 - $33.000.00%
5109Able View Global Inc.ABLV$2.40+3.36%120.88K$58.97M$0.54 - $2.960.00%
5110Tango Therapeutics, Inc.TNGX$24.29+6.82%3.75M$4.10B$7.49 - $34.390.00%
5111Century Therapeutics, Inc.IPSC$1.69-7.18%646.14K$305.11M$0.43 - $3.040.00%
5112LB Pharmaceuticals Inc.LBRX$44.91-0.40%338.88K$1.36B$14.32 - $50.160.00%
5113Revolution Medicines, Inc.RVMD$193.16-3.50%1.44M$41.78B$61.50 - $224.310.00%
5114AbCellera Biologics Inc.ABCL$12.45-0.24%3.54M$3.82B$2.75 - $15.020.00%
5115Entravision CommunicationEVC$9.10-2.04%1.33M$754.88M$2.56 - $13.740.02%
5116ImmunityBio, Inc.IBRX$6.75-5.13%18.73M$7.15B$1.95 - $12.430.00%
5117RF Acquisition Corp IIRFAI$33.80+7.78%4.93K$118.74M$8.94 - $73.000.00%
5118Sandisk CorporationSNDK$859.76-2.98%12.21M$118.82B$183.00 - $2,354.390.00%
5119GIBO Holdings LimitedGIBO$149.60-21.89%11.43K$456.50M$22.60 - $194.910.00%
5120Relay Therapeutics, Inc.RLAY$19.92-2.11%1.90M$4.40B$5.95 - $21.270.00%
5121Vera Bradley, Inc.VRA$8.00-0.75%543.00K$229.60M$1.39 - $8.350.00%
5122Iovance Biotherapeutics, Inc.IOVA$8.08-1.04%8.70M$3.66B$2.08 - $15.370.00%
5123OmniAb, Inc.OABI$5.10-3.77%1.57M$743.30M$1.35 - $5.450.00%
5124Ampco-Pittsburgh Corp.AP$6.72+13.33%156.14K$138.93M$1.75 - $12.810.00%
5125Nuvectis Pharma, Inc.NVCT$20.97+0.29%175.12K$721.27M$5.77 - $29.270.00%
5126Alpha Tau Medical Ltd.DRTS$13.71-2.91%391.59K$1.24B$3.43 - $15.790.00%
5127MaxLinear, Inc.MXL$53.77-3.84%1.94M$4.89B$12.77 - $128.300.00%
5128Pulse Biosciences, Inc.PLSE$55.08-5.28%455.60K$4.05B$12.56 - $58.940.00%
5129Quhuo LimitedQH$3.07+8.43%12.46K$7.43M$0.07 - $12.810.00%
5130AN2 Therapeutics, Inc.ANTX$4.33+8.50%252.78K$163.40M$1.00 - $7.190.00%
513110x Genomics, Inc.TXG$62.87-3.34%2.02M$7.56B$15.12 - $102.810.00%
5132AXT Inc.AXTI$39.30-8.40%8.52M$2.58B$8.44 - $143.160.00%
5133MindForge Inc.MF$16.16-0.52%181.34K$67.76M$3.80 - $25.900.00%
5134Q32 Bio Inc.QTTB$9.34+1.39%295.29K$279.43M$1.91 - $23.570.00%
5135Oruka Therapeutics, Inc.ORKA$109.78+4.99%2.45M$7.27B$25.23 - $115.520.00%
5136PACS Group, Inc.PACS$49.11+0.68%520.91K$7.79B$10.31 - $51.680.01%
5137Veradermics, IncorporatedMANE$148.57+2.52%561.67K$5.80B$32.00 - $152.350.00%
5138Fossil Group, Inc.FOSL$7.90+20.47%978.51K$467.31M$1.70 - $8.250.00%
5139Eton Pharmaceutcials, Inc.ETON$67.60+4.91%1.08M$1.95B$14.27 - $68.320.00%
5140Anterix Inc.ATEX$75.91-6.36%259.32K$1.49B$17.82 - $113.000.00%
5141Energys Group LimitedENGS$4.95+5.10%10.89M$268.23M$0.57 - $5.000.00%
5142Twist Bioscience CorporationTWST$132.07-2.48%1.48M$8.28B$23.30 - $219.710.00%
5143Avita Medical, Inc.RCEL$17.64+2.89%811.31K$554.25M$3.22 - $18.430.00%
5144Spyre Therapeutics, Inc.SYRE$104.46-4.18%809.03K$9.92B$21.63 - $110.640.00%
5145New Century Logistics (BVI) LimitedNCEW$16.96-1.45%73$54.26M$2.80 - $20.830.00%
5146Vince Holding Corp.VNCE$12.87-1.83%205.54K$166.53M$1.95 - $13.900.00%
5147CareDx, Inc.CDNA$80.86-4.38%879.31K$4.25B$15.15 - $90.870.00%
5148BUUU Group LimitedBUUU$4.29-8.72%286.60K$1.05B$0.57 - $8.100.00%
5149Space Exploration Technologies Corp.SPCX$143.15+0.72%77.44M$1.82T$21.32 - $225.640.00%
5150SELLAS Life Sciences Group, Inc.SLS$8.36-2.45%3.46M$1.69B$1.39 - $15.880.00%

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Frequently Asked Questions (FAQ)

What are 52-week top losing U.S. stocks?
These are U.S. stocks that have recorded some of the largest price declines over the past 52 weeks.
How is the 52-week decline measured?
It compares the latest available stock price with its price around 52 weeks earlier and calculates the percentage change.
Which stock has fallen the most over 52 weeks?
Butterfly Network, Inc. (BFLY) currently shows a 52-week decline of 193.15% as of 2026-11-11 00:51 UTC.
Why track 52-week stock losers?
The ranking helps identify stocks facing prolonged price weakness and provides a starting point for further company and valuation research.
Is a 52-week loser automatically a value stock?
No. A lower stock price does not necessarily mean a company is undervalued, so valuation and fundamental data should be reviewed separately.
How is this different from Top Losers?
52-Week Losers measures longer-term performance, while Top Losers focuses on shorter-term market declines.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.