Buy Crypto
Markets
Spot
FuturesBTC
Earn
Event Center
Rewards Hub
More
100%+ PoR

52-Week Top Gaining U.S. stocks

Track U.S. stocks with the strongest price gains over the past 52 weeks on MEXC. Stocks are ranked by their 52-week percentage change to highlight leading one-year performers.

52-Week Top Gaining U.S. stocks

Market Overview

U.S. stocks are broadly lower today, with the Dow Jones down ⁦0.30%⁩, the S&P 500 down ⁦0.38%⁩, and the Nasdaq Composite down ⁦0.74%⁩. Market breadth is negative, with 4,745 stocks declining versus 365 advancing, pointing to a broadly bearish bias.

Dow Jones
52,231.89
Change
-157.86-0.30%
S&P 500
7,520.93
Change
-29.01-0.38%
Nasdaq Composite
25,065.874
Change
-187.265-0.74%
24H Gainers
365
24H Losers
4,745

52 Week Gainers

#Stock52 Week Range
1701Denali Therapeutics Inc.DNLI$19.90+0.25%3.32K$3.19B$15.18 - $27.300.00%
1702Bank OZKOZK$50.87+0.37%0$5.77B$42.37 - $53.390.00%
1703Waste Connections, Inc.WCN$189.50-0.13%424$47.31B$146.89 - $195.340.01%
1704GE HealthCare Technologies Inc.GEHC$83.08-0.95%9.72K$37.56B$58.75 - $89.770.00%
1705Artiva Biotherapeutics, Inc.ARTV$4.060.00%203$198.49M$2.96 - $14.530.00%
1706Biodesix, Inc.BDSX$9.43-4.25%26$99.50M$5.26 - $31.970.00%
1707Williams Companies Inc.WMB$68.42+1.25%91.22K$85.54B$58.09 - $80.080.03%
1708Sanara MedTech Inc.SMTI$31.66+0.06%0$290.88M$16.05 - $35.520.00%
1709Allegion Public Limited CompanyALLE$189.10-0.31%217$15.94B$125.00 - $195.420.01%
1710The Scotts Miracle-Gro CompanySMG$65.39+1.62%130$3.80B$47.90 - $75.340.04%
1711Ingersoll Rand Inc.IR$87.25+0.75%152$33.51B$68.07 - $100.960.00%
1712NextPlat Corp.NXPL$8.480.00%0$23.01M$3.38 - $9.940.00%
1713OP Bancorp.OPBK$14.87-0.17%0$222.05M$12.41 - $16.830.03%
1714FirstCash Holdings, Inc.FCFS$183.280.00%25$7.86B$146.95 - $238.930.01%
1715Verizon CommunicationsVZ$45.90-0.91%1.69M$190.22B$10.60 - $51.680.06%
1716Aurora Cannabis Inc.ACB$5.13-0.48%3.07K$337.17M$2.56 - $6.360.00%
1717MarshMRSH$206.50-1.64%9.83K$98.19B$156.60 - $214.000.02%
1718Fluor CorporationFLR$51.09+2.10%2.32K$6.83B$39.33 - $58.350.00%
1719IRulya Therapeutics Inc.IRLA$36.49-4.70%190$395.66M$25.13 - $41.000.00%
17203M CompanyMMM$189.97-0.04%2.85K$98.17B$139.34 - $196.900.02%
1721Bladex, Inc.BLX$49.67-2.03%1$1.49B$42.29 - $63.200.00%
1722Cheniere Energy Partners, LPCQP$60.25+0.47%31$29.17B$51.47 - $71.250.07%
1723Snowflake Inc.SNOW$305.45+3.17%40.15K$107.76B$118.30 - $384.560.00%
1724Ameriprise Financial, Inc.AMP$523.57+0.03%490$45.45B$422.37 - $572.560.01%
1725Generate Biomedicines, Inc.GENB$14.24+1.60%1.48K$1.68B$11.00 - $22.670.00%
1726Restaurant Brands International Inc.QSR$77.57-0.07%115$27.04B$65.42 - $81.960.04%
1727Oshkosh Corp.OSK$140.130.00%13$8.54B$116.77 - $180.490.02%
1728Valvoline Inc.VVV$35.670.00%0$4.55B$26.21 - $41.080.00%
1729Becton, Dickinson and Co.BDX$212.65-1.51%1.15K$58.59B$140.11 - $216.740.02%
1730Procter & Gamble CompanyPG$167.09-1.28%10.59K$387.28B$137.62 - $170.520.03%
1731Banner Corp.BANR$69.64+0.01%216$2.54B$57.05 - $74.840.03%
1732Blackrock, Inc.BLK$1,220.46+0.01%294$188.47B$917.39 - $1,242.120.02%
1733Liberty Media CorporationFWONA$103.890.00%0$2.49B$73.70 - $104.020.00%
1734Laureate Education, Inc.LAUR$35.010.00%361$4.75B$24.98 - $40.920.00%
1735Preferred BankPFBC$103.73+2.12%0$1.37B$81.50 - $112.260.00%
1736Wd-40 CoWDFC$225.120.00%0$3.01B$175.38 - $298.900.02%
1737Weatherford International plcWFRD$85.59+1.51%209$6.20B$68.49 - $113.150.01%
1738COPT Defense PropertiesCDP$32.82-1.94%0$3.72B$27.05 - $38.900.04%
1739Transact Technologies Inc.TACT$4.850.00%0$50.07M$3.06 - $6.020.00%
1740Barrick Mining CorporationB$40.20+1.11%89.56K$65.47B$34.03 - $54.690.00%
1741OGE Energy Corp.OGE$50.93+0.55%0$10.53B$41.70 - $51.600.03%
1742Maze Therapeutics, Inc.MAZE$36.21+2.10%27$1.90B$21.95 - $53.650.00%
1743Intellia Therapeutics, Inc.NTLA$11.42+1.61%10.24K$1.60B$7.95 - $18.480.00%
1744Neurocrine Biosciences Inc.NBIX$165.16-3.13%262$16.72B$122.14 - $186.120.00%
1745Axos Financial, Inc.AX$91.870.00%203$5.21B$74.89 - $105.740.00%
1746Landstar System Inc.LSTR$145.71+0.07%10$4.91B$121.11 - $228.460.03%
1747DocuSign, Inc.DOCU$77.19+0.01%876$14.43B$40.16 - $85.900.00%
1748Dominion Energy, Inc.D$68.61+0.12%78$60.35B$55.85 - $72.990.04%
1749KENON HOLDINGS LTD.KEN$62.41+1.21%7$3.25B$54.56 - $95.930.00%
1750U-Haul Holding CompanyUHAL$58.90+8.57%1$1.13B$41.95 - $76.450.00%

BTC $81K: Catch the Next Move

Track ETH, SOL & TON rotation signals

BTC $81K: Catch the Next Move

Trade U.S. stocks Your Way on MEXC

RealStocksTokenized StocksStock Futures
What it isRealStocks — real shares of U.S.-listed companiesBlockchain-based tokens linked to U.S. stocks/ETFsUSDT-margined futures on U.S. stock price movements
OwnershipYes — actual sharesNo — synthetic exposure onlyNo — derivative exposure only
Shareholder rightsYes (e.g. dividends)NoNo
Trading hoursU.S. market sessions (pre-market, regular, after-hours, overnight)24/7Up to 24/7 (supported pairs)
Position typesBuy and holdBuy and holdLong, short, leveraged
Best forLong-term investors seeking ownership and dividend incomeTraders wanting round-the-clock access to stock exposure without holding sharesActive/short-term traders looking to speculate or hedge with leverage

Why Trade U.S. stocks on MEXC?

RealStocks, Real Ownership

Buy real US-listed shares through MEXC's partner licensed broker and receive applicable shareholder benefits, including dividends.

7,000+ U.S. stocks & ETFs

Access 7,000+ US-listed stocks and ETFs across technology, finance, healthcare, consumer sectors, and more.

Seamless USDT-to-Stock Access

Transfer USDT and convert between USDT and USD to fund your RealStocks account with ease.

Lower-Cost Stock Trading

Trade real U.S. stocks with competitive costs and keep more capital available for your investment strategy.

Frequently Asked Questions (FAQ)

What are 52-week top gaining U.S. stocks?
These are U.S. stocks with some of the strongest price gains over the past 52 weeks, providing a view of longer-term stock performance.
How is the 52-week gain calculated?
It compares a stock's latest available price with its price roughly 52 weeks earlier and expresses the change as a percentage.
Which stock has gained the most over 52 weeks?
Denali Therapeutics Inc. (DNLI) currently leads with a 52-week gain of 13.19% as of 2026-11-11 13:25 UTC.
Why use a 52-week stock performance ranking?
It helps users identify stocks with sustained price strength over a longer period rather than focusing only on daily market moves.
Does strong 52-week performance guarantee future gains?
No. Historical stock performance does not determine future returns and should be considered alongside company fundamentals and current market conditions.
How is this different from the daily Top Gainers list?
The 52-week ranking focuses on one-year performance, while Top Gainers highlights shorter-term price movements.

Discover Top US Stocks

Disclaimer

US stock prices, indices, rankings, charts, and other market data displayed on this page may be sourced from third-party providers and may be delayed or inaccurate. MEXC provides this information for informational and educational purposes only and does not guarantee its accuracy or completeness. Nothing on this page constitutes financial or investment advice or a recommendation to buy or sell any security. US stock trading involves risk, and past performance does not guarantee future results. Users should conduct independent research before making investment decisions.